PDB 2ow9

PDB Information

PDB2OW9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.
Johnson, A.R., Pavlovsky, A.G., Ortwine, D.F., Prior, F., Man, C.F., Bornemeier, D.A., Banotai, C.A., Mueller, W.T., McConnell, P., Yan, C., Baragi, V., Lesch, C., Roark, W.H., Wilson, M., Datta, K., Guzman, R., Han, H.K., Dyer, R.D.
J.Biol.Chem.
HeaderHydrolase
Released2007-02-15
Resolution1.740
CATH Insert Date28 Feb, 2007

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2007 Chopped
B 28 Feb, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ow9A00 15 Jul, 2007 3.40.390.10 Assigned
2ow9B00 15 Jul, 2007 3.40.390.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P45452 MMP13_HUMAN Homo sapiens Collagenase 3
P45452 MMP13_HUMAN Homo sapiens Collagenase 3