Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck: Synthesis, SAR, and in Vivo Anti-Inflammatory Activity
DiMauro, E.F., Newcomb, J., Nunes, J.J., Bemis, J.E., Boucher, C., Buchanan, J.L., Buckner, W.H., Cee, V.J., Chai, L., Deak, H.L., Epstein, L.F., Faust, T., Gallant, P., Geuns-Meyer, S.D., Gore, A., Gu, Y., Henkle, B., Hodous, B.L., Hsieh, F., Huang, X., Kim, J.L., Lee, J.H., Martin, M.W., Masse, C.E., McGowan, D.C., Metz, D., Mohn, D., Morgenstern, K.A., Oliveira-dos-Santos, A., Patel, V.F., Powers, D., Rose, P.E., Schneider, S., Tomlinson, S.A., Tudor, Y.-Y., Turci, S.M., Welcher, A.A., White, R.D., Zhao, H., Zhu, L., Zhu, X.
J.Med.Chem.