PDB 2oag

PDB Information

PDB2OAG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.
Backes, B.J., Longenecker, K., Hamilton, G.L., Stewart, K., Lai, C., Kopecka, H., von Geldern, T.W., Madar, D.J., Pei, Z., Lubben, T.H., Zinker, B.A., Tian, Z., Ballaron, S.J., Stashko, M.A., Mika, A.K., Beno, D.W., Kempf-Grote, A.J., Black-Schaefer, C., Sham, H.L., Trevillyan, J.M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2006-12-15
Resolution2.300
CATH Insert Date07 Nov, 2007

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 08 Nov, 2007 Chopped
B 08 Nov, 2007 Chopped
C 08 Nov, 2007 Chopped
D 08 Nov, 2007 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2oagA01 23 Nov, 2007 3.40.50.1820 Assigned
2oagA02 23 Nov, 2007 2.140.10.30 Assigned
2oagB01 23 Nov, 2007 3.40.50.1820 Assigned
2oagB02 23 Nov, 2007 2.140.10.30 Assigned
2oagC01 23 Nov, 2007 3.40.50.1820 Assigned
2oagC02 23 Nov, 2007 2.140.10.30 Assigned
2oagD01 23 Nov, 2007 3.40.50.1820 Assigned
2oagD02 23 Nov, 2007 2.140.10.30 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4