PDB Information

PDB2OAE
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Pyrrolidine-constrained phenethylamines: The design of potent, selective, and pharmacologically efficacious dipeptidyl peptidase IV (DPP4) inhibitors from a lead-like screening hit.
Backes, B.J., Longenecker, K., Hamilton, G.L., Stewart, K., Lai, C., Kopecka, H., von Geldern, T.W., Madar, D.J., Pei, Z., Lubben, T.H., Zinker, B.A., Tian, Z., Ballaron, S.J., Stashko, M.A., Mika, A.K., Beno, D.W., Kempf-Grote, A.J., Black-Schaefer, C., Sham, H.L., Trevillyan, J.M.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2006-12-15
Resolution3.000
CATH Insert Date28 Feb, 2007

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 28 Feb, 2007 Chopped
B 28 Feb, 2007 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2oaeA01 13 Jul, 2007 3.40.50.1820 Assigned
2oaeA02 13 Jul, 2007 2.140.10.30 Assigned
2oaeB01 14 Jul, 2007 3.40.50.1820 Assigned
2oaeB02 14 Jul, 2007 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P14740 DPP4_RAT Rattus norvegicus Dipeptidyl peptidase 4
P14740 DPP4_RAT Rattus norvegicus Dipeptidyl peptidase 4