PDB 2jc1

PDB Links
Overview

PDB Information

PDB	2JC1
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HEPATITIS C VIRUS
Primary Citation	Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. Slater, M.J., Amphlett, E.M., Andrews, D.M., Bravi, G., Burton, G., Cheasty, A.G., Corfield, J.A., Ellis, M.R., Fenwick, R.H., Fernandes, S., Guidetti, R., Haigh, D., Hartley, C.D., Howes, P.D., Jackson, D.L., Jarvest, R.L., Lovegrove, V.L., Medhurst, K.J., Parry, N.R., Price, H., Shah, P., Singh, O.M., Stocker, R., Thommes, P., Wilkinson, C., Wonacott, A. J.Med.Chem.
Header	Hydrolase
Released	2006-12-18
Resolution	2.000
CATH Insert Date	23 Feb, 2007

PDB Images (11)

Image of CATH 2jc1

2jc1

PDB 2jc1

Image of CATH 2jc1A

2jc1A

PDB Chain 2jc1A

Image of CATH 2jc1B

2jc1B

PDB Chain 2jc1B

Image of CATH 2jc1A01

2jc1A01

CATH Domain 2jc1A01

Image of CATH 2jc1A02

2jc1A02

CATH Domain 2jc1A02

Image of CATH 2jc1A03

2jc1A03

CATH Domain 2jc1A03

Image of CATH 2jc1A04

2jc1A04

CATH Domain 2jc1A04

Image of CATH 2jc1B01

2jc1B01

CATH Domain 2jc1B01

Image of CATH 2jc1B02

2jc1B02

CATH Domain 2jc1B02

Image of CATH 2jc1B03

2jc1B03

CATH Domain 2jc1B03

Image of CATH 2jc1B04

2jc1B04

CATH Domain 2jc1B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	23 Feb, 2007	Chopped
B	23 Feb, 2007	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2jc1A01	27 Sep, 2013		Holding pen
2jc1A02	27 Sep, 2013		Holding pen
2jc1A03	27 Sep, 2013	3.30.70.270	Assigned
2jc1A04	27 Sep, 2013		Holding pen
2jc1B01	27 Sep, 2013		Holding pen
2jc1B02	27 Sep, 2013		Holding pen
2jc1B03	27 Sep, 2013	3.30.70.270	Assigned
2jc1B04	27 Sep, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein