PDB 2jc0

PDB Links
Overview

PDB Information

PDB	2JC0
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HEPATITIS C VIRUS
Primary Citation	Optimization of Novel Acyl Pyrrolidine Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase Leading to a Development Candidate. Slater, M.J., Amphlett, E.M., Andrews, D.M., Bravi, G., Burton, G., Cheasty, A.G., Corfield, J.A., Ellis, M.R., Fenwick, R.H., Fernandes, S., Guidetti, R., Haigh, D., Hartley, C.D., Howes, P.D., Jackson, D.L., Jarvest, R.L., Lovegrove, V.L., Medhurst, K.J., Parry, N.R., Price, H., Shah, P., Singh, O.M., Stocker, R., Thommes, P., Wilkinson, C., Wonacott, A. J.Med.Chem.
Header	Hydrolase
Released	2006-12-18
Resolution	2.200
CATH Insert Date	23 Feb, 2007

PDB Images (11)

Image of CATH 2jc0

2jc0

PDB 2jc0

Image of CATH 2jc0A

2jc0A

PDB Chain 2jc0A

Image of CATH 2jc0B

2jc0B

PDB Chain 2jc0B

Image of CATH 2jc0A01

2jc0A01

CATH Domain 2jc0A01

Image of CATH 2jc0A02

2jc0A02

CATH Domain 2jc0A02

Image of CATH 2jc0A03

2jc0A03

CATH Domain 2jc0A03

Image of CATH 2jc0A04

2jc0A04

CATH Domain 2jc0A04

Image of CATH 2jc0B01

2jc0B01

CATH Domain 2jc0B01

Image of CATH 2jc0B02

2jc0B02

CATH Domain 2jc0B02

Image of CATH 2jc0B03

2jc0B03

CATH Domain 2jc0B03

Image of CATH 2jc0B04

2jc0B04

CATH Domain 2jc0B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	23 Feb, 2007	Chopped
B	23 Feb, 2007	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2jc0A01	27 Sep, 2013		Holding pen
2jc0A02	27 Sep, 2013		Holding pen
2jc0A03	27 Sep, 2013	3.30.70.270	Assigned
2jc0A04	27 Sep, 2013		Holding pen
2jc0B01	26 Sep, 2013		Holding pen
2jc0B02	26 Sep, 2013		Holding pen
2jc0B03	26 Sep, 2013	3.30.70.270	Assigned
2jc0B04	26 Sep, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein
P26663	POLG_HCVBK	Hepatitis C virus (isolate BK)	Genome polyprotein