PDB 2j50

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Overview

PDB Information

PDB	2J50
Method	X-RAY DIFFRACTION
Host Organism	SPODOPTERA FRUGIPERDA
Gene Source	HOMO SAPIENS
Primary Citation	1,4,5,6-Tetrahydropyrrolo[3,4-C]Pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile. Fancelli, D., Moll, J., Varasi, M., Bravo, R., Artico, R., Berta, D., Bindi, S., Cameron, A.D., Candiani, I., Cappella, P., Carpinelli, P., Croci, W., Forte, B., Giorgini, M.L., Klapwijk, J., Marsiglio, A., Pesenti, E., Rocchetti, M., Roletto, F., Severino, D., Soncini, C., Storici, P., Tonani, R., Zugnoni, P., Vianello, P. J.Med.Chem.
Header	Transferase
Released	2006-09-08
Resolution	3.000
CATH Insert Date	16 Nov, 2006

PDB Images (7)

Image of CATH 2j50

2j50

PDB 2j50

Image of CATH 2j50A

2j50A

PDB Chain 2j50A

Image of CATH 2j50B

2j50B

PDB Chain 2j50B

Image of CATH 2j50A01

2j50A01

CATH Domain 2j50A01

Image of CATH 2j50A02

2j50A02

CATH Domain 2j50A02

Image of CATH 2j50B01

2j50B01

CATH Domain 2j50B01

Image of CATH 2j50B02

2j50B02

CATH Domain 2j50B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	16 Nov, 2006	Chopped
B	16 Nov, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2j50A01	14 Jul, 2007	3.30.200.20	Assigned
2j50A02	14 Jul, 2007	1.10.510.10	Assigned
2j50B01	14 Jul, 2007	3.30.200.20	Assigned
2j50B02	14 Jul, 2007	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A
O14965	AURKA_HUMAN	Homo sapiens	Aurora kinase A