PDB 2iit

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Overview

PDB Information

PDB	2IIT
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	(3R)-4-[(3R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(2,2,2-trifluoroethyl)-1,4-diazepan-2-one, a selective dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes Biftu, T., Feng, D., Qian, X., Liang, G.B., Kieczykowski, G., Eiermann, G., He, H., Leiting, B., Lyons, K., Petrov, A., Sinha-Roy, R., Zhang, B., Scapin, G., Patel, S., Gao, Y.D., Singh, S., Wu, J., Zhang, X., Thornberry, N.A., Weber, A.E. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2006-09-28
Resolution	2.350
CATH Insert Date	07 Jan, 2007

PDB Images (7)

Image of CATH 2iit

2iit

PDB 2iit

Image of CATH 2iitA

2iitA

PDB Chain 2iitA

Image of CATH 2iitB

2iitB

PDB Chain 2iitB

Image of CATH 2iitA01

2iitA01

CATH Domain 2iitA01

Image of CATH 2iitA02

2iitA02

CATH Domain 2iitA02

Image of CATH 2iitB01

2iitB01

CATH Domain 2iitB01

Image of CATH 2iitB02

2iitB02

CATH Domain 2iitB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	07 Jan, 2007	Chopped
B	07 Jan, 2007	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2iitA01	09 Jan, 2007	3.40.50.1820	Assigned
2iitA02	09 Jan, 2007	2.140.10.30	Assigned
2iitB01	09 Jan, 2007	3.40.50.1820	Assigned
2iitB02	09 Jan, 2007	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4