PDB 2i4q

PDB Information

PDB2I4Q
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors.
Powell, N.A., Ciske, F.L., Cai, C., Holsworth, D.D., Mennen, K., Van Huis, C.A., Jalaie, M., Day, J., Mastronardi, M., McConnell, P., Mochalkin, I., Zhang, E., Ryan, M.J., Bryant, J., Collard, W., Ferreira, S., Gu, C., Collins, R., Edmunds, J.J.
Bioorg.Med.Chem.
HeaderHydrolase
Released2006-08-22
Resolution2.300
CATH Insert Date26 Oct, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 26 Oct, 2006 Chopped
B 26 Oct, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2i4qA01 13 Dec, 2006 2.40.70.10 Assigned
2i4qA02 13 Dec, 2006 2.40.70.10 Assigned
2i4qB01 13 Dec, 2006 2.40.70.10 Assigned
2i4qB02 13 Dec, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00797 RENI_HUMAN Homo sapiens Renin
P00797 RENI_HUMAN Homo sapiens Renin