PDB Information

PDB2I40
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase
Bamborough, P., Christopher, J.A., Cutler, G.J., Dickson, M.C., Mellor, G.W., Morey, J.V., Patel, C.B., Shewchuk, L.M.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Cell Cycle
Released2006-08-21
Resolution2.800
CATH Insert Date12 Oct, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 12 Oct, 2006 Chopped
B 12 Oct, 2006 Chopped
C 12 Oct, 2006 Chopped
D 12 Oct, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2i40A01 19 Jul, 2007 3.30.200.20 Assigned
2i40A02 19 Jul, 2007 1.10.510.10 Assigned
2i40B01 14 Jul, 2007 1.10.472.10 Assigned
2i40B02 14 Jul, 2007 1.10.472.10 Assigned
2i40C01 18 Jul, 2007 3.30.200.20 Assigned
2i40C02 18 Jul, 2007 1.10.510.10 Assigned
2i40D01 14 Jul, 2007 1.10.472.10 Assigned
2i40D02 14 Jul, 2007 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2