PDB 2i3i

PDB Information

PDB2I3I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
Zobel, K., Wang, L., Varfolomeev, E., Franklin, M.C., Elliott, L.O., Wallweber, H.J., Okawa, D.C., Flygare, J.A., Vucic, D., Fairbrother, W.J., Deshayes, K.
Acs Chem.Biol.
HeaderInhibitor/Apoptosis
Released2006-08-18
Resolution2.300
CATH Insert Date21 Sep, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2006 Chopped
B 21 Sep, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2i3iA00 16 Oct, 2006 1.10.1170.10 Assigned
2i3iB00 16 Oct, 2006 1.10.1170.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q96CA5 BIRC7_HUMAN Homo sapiens Baculoviral IAP repeat-containing protein 7
Q96CA5 BIRC7_HUMAN Homo sapiens Baculoviral IAP repeat-containing protein 7