PDB 2hog

PDB Information

PDB2HOG
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.
Fraley, M.E., Steen, J.T., Brnardic, E.J., Arrington, K.L., Spencer, K.L., Hanney, B.A., Kim, Y., Hartman, G.D., Stirdivant, S.M., Drakas, B.A., Rickert, K., Walsh, E.S., Hamilton, K., Buser, C.A., Hardwick, J., Tao, W., Beck, S.C., Mao, X., Lobell, R.B., Sepp-Lorenzino, L., Yan, Y., Ikuta, M., Munshi, S.K., Kuo, L.C., Kreatsoulas, C.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2006-07-14
Resolution1.900
CATH Insert Date26 Apr, 2007

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 26 Apr, 2007 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2hogA01 14 Jul, 2007 3.30.200.20 Assigned
2hogA02 14 Jul, 2007 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
O14757 CHK1_HUMAN Homo sapiens Serine/threonine-protein kinase Chk1