PDB 2hiz

PDB Links
Overview

PDB Information

PDB	2HIZ
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Design of potent inhibitors of human beta-secretase. Part 1. Freskos, J.N., Fobian, Y.M., Benson, T.E., Bienkowski, M.J., Brown, D.L., Emmons, T.L., Heintz, R., Laborde, A., McDonald, J.J., Mischke, B.V., Molyneaux, J.M., Moon, J.B., Mullins, P.B., Bryan Prince, D., Paddock, D.J., Tomasselli, A.G., Winterrowd, G. Bioorg.Med.Chem.Lett.
Header	Hydrolase
Released	2006-06-29
Resolution	2.500
CATH Insert Date	23 Feb, 2007

PDB Images (10)

Image of CATH 2hiz

2hiz

PDB 2hiz

Image of CATH 2hizA

2hizA

PDB Chain 2hizA

Image of CATH 2hizB

2hizB

PDB Chain 2hizB

Image of CATH 2hizC

2hizC

PDB Chain 2hizC

Image of CATH 2hizA01

2hizA01

CATH Domain 2hizA01

Image of CATH 2hizA02

2hizA02

CATH Domain 2hizA02

Image of CATH 2hizB01

2hizB01

CATH Domain 2hizB01

Image of CATH 2hizB02

2hizB02

CATH Domain 2hizB02

Image of CATH 2hizC01

2hizC01

CATH Domain 2hizC01

Image of CATH 2hizC02

2hizC02

CATH Domain 2hizC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	23 Feb, 2007	Chopped
B	23 Feb, 2007	Chopped
C	23 Feb, 2007	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2hizA01	14 Jul, 2007	2.40.70.10	Assigned
2hizA02	14 Jul, 2007	2.40.70.10	Assigned
2hizB01	15 Jul, 2007	2.40.70.10	Assigned
2hizB02	15 Jul, 2007	2.40.70.10	Assigned
2hizC01	14 Jul, 2007	2.40.70.10	Assigned
2hizC02	14 Jul, 2007	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1