PDB 2hfp

PDB Information

PDB2HFP
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosis.
Hopkins, C.R., O'neil, S.V., Laufersweiler, M.C., Wang, Y., Pokross, M., Mekel, M., Evdokimov, A., Walter, R., Kontoyianni, M., Petrey, M.E., Sabatakos, G., Roesgen, J.T., Richardson, E., Demuth Jr., T.P.
Bioorg.Med.Chem.Lett.
HeaderTranscription
Released2006-06-25
Resolution2.000
CATH Insert Date21 Sep, 2006

PDB Images (4)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 21 Sep, 2006 Chopped
B 21 Sep, 2006 Rejected

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2hfpA00 16 Oct, 2006 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q15788 NCOA1_HUMAN Homo sapiens Nuclear receptor coactivator 1
P37231 PPARG_HUMAN Homo sapiens Peroxisome proliferator-activated receptor gamma