PDB 2h8h

PDB Links
Overview

PDB Information

PDB	2H8H
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5- (tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine, a novel, highly selective, orally available, dual-specific c-Src/Abl kinase inhibitor. Hennequin, L.F., Allen, J., Breed, J., Curwen, J., Fennell, M., Green, T.P., Lambert-van der Brempt, C., Morgentin, R., Norman, R.A., Olivier, A., Otterbein, L., Ple, P.A., Warin, N., Costello, G. J.Med.Chem.
Header	Transferase
Released	2006-06-07
Resolution	2.200
CATH Insert Date	23 Nov, 2006

PDB Images (6)

Image of CATH 2h8h

2h8h

PDB 2h8h

Image of CATH 2h8hA

2h8hA

PDB Chain 2h8hA

Image of CATH 2h8hA01

2h8hA01

CATH Domain 2h8hA01

Image of CATH 2h8hA02

2h8hA02

CATH Domain 2h8hA02

Image of CATH 2h8hA03

2h8hA03

CATH Domain 2h8hA03

Image of CATH 2h8hA04

2h8hA04

CATH Domain 2h8hA04

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	23 Nov, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2h8hA01	10 Sep, 2008	2.30.30.40	Assigned
2h8hA02	10 Sep, 2008	3.30.505.10	Assigned
2h8hA03	10 Sep, 2008	3.30.200.20	Assigned
2h8hA04	10 Sep, 2008	1.10.510.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P12931	SRC_HUMAN	Homo sapiens	Proto-oncogene tyrosine-protein kinase Src