PDB 2gm1

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Overview

PDB Information

PDB	2GM1
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21(DE3)
Gene Source	Homo sapiens
Primary Citation	Synthesis and SAR of pyrrolotriazine-4-one based Eg5 inhibitors. Kim, K.S., Lu, S., Cornelius, L.A., Lombardo, L.J., Borzilleri, R.M., Schroeder, G.M., Sheng, C., Rovnyak, G., Crews, D., Schmidt, R.J., Williams, D.K., Bhide, R.S., Traeger, S.C., McDonnell, P.A., Mueller, L., Sheriff, S., Newitt, J.A., Pudzianowski, A.T., Yang, Z., Wild, R., Lee, F.Y., Batorsky, R., Ryder, J.S., Ortega-Nanos, M., Shen, H., Gottardis, M., Roussell, D.L. Bioorg.Med.Chem.Lett.
Header	Cell Cycle
Released	2006-04-05
Resolution	2.300
CATH Insert Date	14 Jul, 2006

PDB Images (9)

Image of CATH 2gm1

2gm1

PDB 2gm1

Image of CATH 2gm1A

2gm1A

PDB Chain 2gm1A

Image of CATH 2gm1B

2gm1B

PDB Chain 2gm1B

Image of CATH 2gm1D

2gm1D

PDB Chain 2gm1D

Image of CATH 2gm1E

2gm1E

PDB Chain 2gm1E

Image of CATH 2gm1A00

2gm1A00

CATH Domain 2gm1A00

Image of CATH 2gm1B00

2gm1B00

CATH Domain 2gm1B00

Image of CATH 2gm1D00

2gm1D00

CATH Domain 2gm1D00

Image of CATH 2gm1E00

2gm1E00

CATH Domain 2gm1E00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	14 Jul, 2006	Chopped
B	14 Jul, 2006	Chopped
D	14 Jul, 2006	Chopped
E	14 Jul, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2gm1A00	02 Nov, 2006	3.40.850.10	Assigned
2gm1B00	02 Nov, 2006	3.40.850.10	Assigned
2gm1D00	02 Nov, 2006	3.40.850.10	Assigned
2gm1E00	02 Nov, 2006	3.40.850.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P52732	KIF11_HUMAN	Homo sapiens	Kinesin-like protein KIF11
P52732	KIF11_HUMAN	Homo sapiens	Kinesin-like protein KIF11
P52732	KIF11_HUMAN	Homo sapiens	Kinesin-like protein KIF11
P52732	KIF11_HUMAN	Homo sapiens	Kinesin-like protein KIF11