PDB 2gc8

PDB Links
Overview

PDB Information

PDB	2GC8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Hepatitis C virus
Primary Citation	Discovery of Proline Sulfonamides as Potent and Selective Hepatitis C Virus NS5b Polymerase Inhibitors. Evidence for a New NS5b Polymerase Binding Site. Gopalsamy, A., Chopra, R., Lim, K., Ciszewski, G., Shi, M., Curran, K.J., Sukits, S.F., Svenson, K., Bard, J., Ellingboe, J.W., Agarwal, A., Krishnamurthy, G., Howe, A.Y., Orlowski, M., Feld, B., O'connell, J., Mansour, T.S. J.Med.Chem.
Header	Transferase
Released	2006-03-13
Resolution	2.200
CATH Insert Date	14 Jul, 2006

PDB Images (11)

Image of CATH 2gc8

2gc8

PDB 2gc8

Image of CATH 2gc8A

2gc8A

PDB Chain 2gc8A

Image of CATH 2gc8B

2gc8B

PDB Chain 2gc8B

Image of CATH 2gc8A01

2gc8A01

CATH Domain 2gc8A01

Image of CATH 2gc8A02

2gc8A02

CATH Domain 2gc8A02

Image of CATH 2gc8A03

2gc8A03

CATH Domain 2gc8A03

Image of CATH 2gc8A04

2gc8A04

CATH Domain 2gc8A04

Image of CATH 2gc8B01

2gc8B01

CATH Domain 2gc8B01

Image of CATH 2gc8B02

2gc8B02

CATH Domain 2gc8B02

Image of CATH 2gc8B03

2gc8B03

CATH Domain 2gc8B03

Image of CATH 2gc8B04

2gc8B04

CATH Domain 2gc8B04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Jul, 2006	Chopped
B	14 Jul, 2006	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2gc8A01	26 Sep, 2013		Holding pen
2gc8A02	26 Sep, 2013		Holding pen
2gc8A03	26 Sep, 2013	3.30.70.270	Assigned
2gc8A04	26 Sep, 2013		Holding pen
2gc8B01	26 Sep, 2013		Holding pen
2gc8B02	26 Sep, 2013		Holding pen
2gc8B03	26 Sep, 2013	3.30.70.270	Assigned
2gc8B04	26 Sep, 2013		Holding pen

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q99AU2	Q99AU2_9HEPC	Hepatitis C virus subtype 1b	Genome polyprotein
Q99AU2	Q99AU2_9HEPC	Hepatitis C virus subtype 1b	Genome polyprotein