PDB 2g5t

PDB Information

PDB2G5T
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
Pei, Z., Li, X., Longenecker, K., Von Geldern, T.W., Wiedeman, P.E., Lubben, T.H., Zinker, B.A., Stewart, K., Ballaron, S.J., Stashko, M.A., Mika, A.K., Beno, D.W., Long, M., Wells, H., Kempf-Grote, A.J., Madar, D.J., McDermott, T.S., Bhagavatula, L., Fickes, M.G., Pireh, D., Solomon, L.R., Lake, M.R., Edalji, R., Fry, E.H., Sham, H.L., Trevillyan, J.M.
J.Med.Chem.
HeaderHydrolase
Released2006-02-23
Resolution2.300
CATH Insert Date14 Jul, 2006

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2g5tA01 02 Nov, 2006 3.40.50.1820 Assigned
2g5tA02 02 Nov, 2006 2.140.10.30 Assigned
2g5tB01 02 Nov, 2006 3.40.50.1820 Assigned
2g5tB02 02 Nov, 2006 2.140.10.30 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4
P27487 DPP4_HUMAN Homo sapiens Dipeptidyl peptidase 4