PDB 2fvd

PDB Information

PDB2FVD
MethodX-RAY DIFFRACTION
Host Organismunidentified baculovirus
Gene SourceHomo sapiens
Primary Citation
Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6- methoxyphenyl)methanone (R547), a potent and selective cyclin-dependent kinase inhibitor with significant in vivo antitumor activity.
Chu, X.J., DePinto, W., Bartkovitz, D., So, S.S., Vu, B.T., Packman, K., Lukacs, C., Ding, Q., Jiang, N., Wang, K., Goelzer, P., Yin, X., Smith, M.A., Higgins, B.X., Chen, Y., Xiang, Q., Moliterni, J., Kaplan, G., Graves, B., Lovey, A., Fotouhi, N.
J.Med.Chem.
HeaderTransferase
Released2006-01-30
Resolution1.850
CATH Insert Date12 Oct, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 12 Oct, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2fvdA01 16 Jul, 2007 3.30.200.20 Assigned
2fvdA02 16 Jul, 2007 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2