PDB 2fjp

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Overview

PDB Information

PDB	2FJP
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	(2S,3S)-3-Amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxo-2-(4-[1,2,4]triazolo[1,5-a]- pyridin-6-ylphenyl)butanamide: a selective alpha-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. Edmondson, S.D., Mastracchio, A., Mathvink, R.J., He, J., Harper, B., Park, Y.J., Beconi, M., Di Salvo, J., Eiermann, G.J., He, H., Leiting, B., Leone, J.F., Levorse, D.A., Lyons, K., Patel, R.A., Patel, S.B., Petrov, A., Scapin, G., Shang, J., Roy, R.S., Smith, A., Wu, J.K., Xu, S., Zhu, B., Thornberry, N.A., Weber, A.E. J.Med.Chem.
Header	Hydrolase
Released	2006-01-03
Resolution	2.400
CATH Insert Date	14 Jul, 2006

PDB Images (7)

Image of CATH 2fjp

2fjp

PDB 2fjp

Image of CATH 2fjpA

2fjpA

PDB Chain 2fjpA

Image of CATH 2fjpB

2fjpB

PDB Chain 2fjpB

Image of CATH 2fjpA01

2fjpA01

CATH Domain 2fjpA01

Image of CATH 2fjpA02

2fjpA02

CATH Domain 2fjpA02

Image of CATH 2fjpB01

2fjpB01

CATH Domain 2fjpB01

Image of CATH 2fjpB02

2fjpB02

CATH Domain 2fjpB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	14 Jul, 2006	Chopped
B	14 Jul, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2fjpA01	01 Nov, 2006	3.40.50.1820	Assigned
2fjpA02	01 Nov, 2006	2.140.10.30	Assigned
2fjpB01	02 Nov, 2006	3.40.50.1820	Assigned
2fjpB02	02 Nov, 2006	2.140.10.30	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4
P27487	DPP4_HUMAN	Homo sapiens	Dipeptidyl peptidase 4