PDB 2fdp

PDB Links
Overview

PDB Information

PDB	2FDP
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli BL21
Gene Source	Homo sapiens
Primary Citation	Aminoethylenes: a tetrahedral intermediate isostere yielding potent inhibitors of the aspartyl protease BACE-1. Yang, W., Lu, W., Lu, Y., Zhong, M., Sun, J., Thomas, A.E., Wilkinson, J.M., Fucini, R.V., Lam, M., Randal, M., Shi, X.P., Jacobs, J.W., McDowell, R.S., Gordon, E.M., Ballinger, M.D. J.Med.Chem.
Header	Hydrolase
Released	2005-12-14
Resolution	2.500
CATH Insert Date	05 Mar, 2006

PDB Images (10)

Image of CATH 2fdp

2fdp

PDB 2fdp

Image of CATH 2fdpA

2fdpA

PDB Chain 2fdpA

Image of CATH 2fdpB

2fdpB

PDB Chain 2fdpB

Image of CATH 2fdpC

2fdpC

PDB Chain 2fdpC

Image of CATH 2fdpA01

2fdpA01

CATH Domain 2fdpA01

Image of CATH 2fdpA02

2fdpA02

CATH Domain 2fdpA02

Image of CATH 2fdpB01

2fdpB01

CATH Domain 2fdpB01

Image of CATH 2fdpB02

2fdpB02

CATH Domain 2fdpB02

Image of CATH 2fdpC01

2fdpC01

CATH Domain 2fdpC01

Image of CATH 2fdpC02

2fdpC02

CATH Domain 2fdpC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped
C	05 Mar, 2006	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2fdpA01	15 Mar, 2006	2.40.70.10	Assigned
2fdpA02	15 Mar, 2006	2.40.70.10	Assigned
2fdpB01	15 Mar, 2006	2.40.70.10	Assigned
2fdpB02	15 Mar, 2006	2.40.70.10	Assigned
2fdpC01	15 Mar, 2006	2.40.70.10	Assigned
2fdpC02	15 Mar, 2006	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1