PDB Information

PDB2FAK
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Crystal Structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in Complex with the 20S Proteasome Reveal Important Consequences of beta-Lactone Ring Opening and a Mechanism for Irreversible Binding.
Groll, M., Huber, R., Potts, B.C.
J.Am.Chem.Soc.
HeaderHydrolase
Released2005-12-07
Resolution2.800
CATH Insert Date14 Jul, 2006

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
1 14 Jul, 2006 Chopped
2 14 Jul, 2006 Chopped
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Chopped
D 14 Jul, 2006 Chopped
E 14 Jul, 2006 Chopped
F 14 Jul, 2006 Chopped
G 14 Jul, 2006 Chopped
H 14 Jul, 2006 Chopped
I 14 Jul, 2006 Chopped
J 14 Jul, 2006 Chopped
K 14 Jul, 2006 Chopped
L 14 Jul, 2006 Chopped
M 14 Jul, 2006 Chopped
N 14 Jul, 2006 Chopped
O 14 Jul, 2006 Chopped
P 14 Jul, 2006 Chopped
Q 14 Jul, 2006 Chopped
R 14 Jul, 2006 Chopped
S 14 Jul, 2006 Chopped
T 14 Jul, 2006 Chopped
U 14 Jul, 2006 Chopped
V 14 Jul, 2006 Chopped
W 14 Jul, 2006 Chopped
X 14 Jul, 2006 Chopped
Y 14 Jul, 2006 Chopped
Z 14 Jul, 2006 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
2fak100 16 Oct, 2006 3.60.20.10 Assigned
2fak200 16 Oct, 2006 3.60.20.10 Assigned
2fakA00 16 Oct, 2006 3.60.20.10 Assigned
2fakB00 16 Oct, 2006 3.60.20.10 Assigned
2fakC00 16 Oct, 2006 3.60.20.10 Assigned
2fakD00 16 Oct, 2006 3.60.20.10 Assigned
2fakE00 16 Oct, 2006 3.60.20.10 Assigned
2fakF00 16 Oct, 2006 3.60.20.10 Assigned
2fakG00 16 Oct, 2006 3.60.20.10 Assigned
2fakH00 16 Oct, 2006 3.60.20.10 Assigned
2fakI00 16 Oct, 2006 3.60.20.10 Assigned
2fakJ00 16 Oct, 2006 3.60.20.10 Assigned
2fakK00 16 Oct, 2006 3.60.20.10 Assigned
2fakL00 16 Oct, 2006 3.60.20.10 Assigned
2fakM00 16 Oct, 2006 3.60.20.10 Assigned
2fakN00 16 Oct, 2006 3.60.20.10 Assigned
2fakO00 16 Oct, 2006 3.60.20.10 Assigned
2fakP00 16 Oct, 2006 3.60.20.10 Assigned
2fakQ00 16 Oct, 2006 3.60.20.10 Assigned
2fakR00 16 Oct, 2006 3.60.20.10 Assigned
2fakS00 16 Oct, 2006 3.60.20.10 Assigned
2fakT00 16 Oct, 2006 3.60.20.10 Assigned
2fakU00 16 Oct, 2006 3.60.20.10 Assigned
2fakV00 16 Oct, 2006 3.60.20.10 Assigned
2fakW00 16 Oct, 2006 3.60.20.10 Assigned
2fakX00 16 Oct, 2006 3.60.20.10 Assigned
2fakY00 16 Oct, 2006 3.60.20.10 Assigned
2fakZ00 16 Oct, 2006 3.60.20.10 Assigned

UniProtKB Entries (28)

Accession Gene ID Taxon Description
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7