PDB Information

PDB2F6W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
1,2,3,4-Tetrahydroisoquinolinyl sulfamic acids as phosphatase PTP1B inhibitors
Klopfenstein, S.R., Evdokimov, A.G., Colson, A.-O., Fairweather, N.T., Neuman, J.J., Maier, M.B., Gray, J.L., Gerwe, G.S., Stake, G.E., Howard, B.W., Farmer, J.A., Pokross, M.E., Downs, T.R., Kasibhatla, B., Peters, K.G.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2005-11-29
Resolution2.2
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2f6wA00 10 Mar, 2006 3.90.190.10 Assigned

Uniprot Entries (1)

Accession Gene ID Taxon Description
P18031 PTN1_HUMAN Homo sapiens Protein-tyrosine phosphatase 1B