PDB 2f54

PDB Information

PDB2F54
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity.
Dunn, S.M., Rizkallah, P.J., Baston, E., Mahon, T., Cameron, B., Moysey, R., Gao, F., Sami, M., Boulter, J., Li, Y., Jakobsen, B.K.
Protein Sci.
HeaderImmune System
Released2005-11-25
Resolution2.700
CATH Insert Date14 Jul, 2006

PDB Images (25)

PDB Prints

PDB Chains (10)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Rejected
D 14 Jul, 2006 Chopped
E 14 Jul, 2006 Chopped
F 14 Jul, 2006 Chopped
G 14 Jul, 2006 Chopped
H 14 Jul, 2006 Rejected
K 14 Jul, 2006 Chopped
L 14 Jul, 2006 Chopped

CATH Domains (14)

Domain ID Date inserted into CATH Superfamily CATH Status
2f54A01 29 Nov, 2006 3.30.500.10 Assigned
2f54A02 29 Nov, 2006 2.60.40.10 Assigned
2f54B00 16 Oct, 2006 2.60.40.10 Assigned
2f54D01 15 Jul, 2007 2.60.40.10 Assigned
2f54D02 15 Jul, 2007 2.60.40.10 Assigned
2f54E01 15 Jul, 2007 2.60.40.10 Assigned
2f54E02 15 Jul, 2007 2.60.40.10 Assigned
2f54F01 29 Nov, 2006 3.30.500.10 Assigned
2f54F02 29 Nov, 2006 2.60.40.10 Assigned
2f54G00 16 Oct, 2006 2.60.40.10 Assigned
2f54K01 15 Jul, 2007 2.60.40.10 Assigned
2f54K02 15 Jul, 2007 2.60.40.10 Assigned
2f54L01 15 Jul, 2007 2.60.40.10 Assigned
2f54L02 15 Jul, 2007 2.60.40.10 Assigned

UniProtKB Entries (10)

Accession Gene ID Taxon Description
P78358 CTG1B_HUMAN Homo sapiens Cancer/testis antigen 1
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant
P78358 CTG1B_HUMAN Homo sapiens Cancer/testis antigen 1
P01850 TRBC1_HUMAN Homo sapiens T cell receptor beta constant 1
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P01892 1A02_HUMAN Homo sapiens HLA class I histocompatibility antigen, A-2 alpha chain
P61769 B2MG_HUMAN Homo sapiens Beta-2-microglobulin
P01850 TRBC1_HUMAN Homo sapiens T cell receptor beta constant 1
P01848 TRAC_HUMAN Homo sapiens T cell receptor alpha constant