PDB 2f3f

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PDB Links
Overview

PDB Information

PDB	2F3F
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structure-based design and synthesis of macroheterocyclic peptidomimetic inhibitors of the aspartic protease beta-site amyloid precursor protein cleaving enzyme (BACE). Hanessian, S., Yang, G., Rondeau, J.-M., Neumann, U., Betschart, C., Tintelnot-Blomley, M. J.Med.Chem.
Header	Hydrolase
Released	2005-11-21
Resolution	2.300
CATH Insert Date	07 Sep, 2006

PDB Images (10)

Image of CATH 2f3f

2f3f

PDB 2f3f

Image of CATH 2f3fA

2f3fA

PDB Chain 2f3fA

Image of CATH 2f3fB

2f3fB

PDB Chain 2f3fB

Image of CATH 2f3fC

2f3fC

PDB Chain 2f3fC

Image of CATH 2f3fA01

2f3fA01

CATH Domain 2f3fA01

Image of CATH 2f3fA02

2f3fA02

CATH Domain 2f3fA02

Image of CATH 2f3fB01

2f3fB01

CATH Domain 2f3fB01

Image of CATH 2f3fB02

2f3fB02

CATH Domain 2f3fB02

Image of CATH 2f3fC01

2f3fC01

CATH Domain 2f3fC01

Image of CATH 2f3fC02

2f3fC02

CATH Domain 2f3fC02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	07 Sep, 2006	Chopped
B	07 Sep, 2006	Chopped
C	07 Sep, 2006	Chopped

CATH Domains (6)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2f3fA01	16 Oct, 2006	2.40.70.10	Assigned
2f3fA02	16 Oct, 2006	2.40.70.10	Assigned
2f3fB01	16 Oct, 2006	2.40.70.10	Assigned
2f3fB02	16 Oct, 2006	2.40.70.10	Assigned
2f3fC01	16 Oct, 2006	2.40.70.10	Assigned
2f3fC02	16 Oct, 2006	2.40.70.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1