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PDB Information

PDB2EA4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Lead optimization of methionine aminopeptidase-2 (MetAP2) inhibitors containing sulfonamides of 5,6-disubstituted anthranilic acids
Wang, G.T., Mantei, R.A., Kawai, M., Tedrow, J.S., Barnes, D.M., Wang, J., Zhang, Q., Lou, P., Garcia, L.A., Bouska, J., Yates, M., Park, C., Judge, R.A., Lesniewski, R., Sheppard, G.S., Bell, R.L.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2007-01-30
Resolution2.350
CATH Insert Date21 Feb, 2008

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 21 Feb, 2008 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2ea4A01 24 Jan, 2013 3.90.230.10 Assigned
2ea4A02 24 Jan, 2013 1.10.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P50579 MAP2_HUMAN Homo sapiens Methionine aminopeptidase 2
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