PDB Information

PDB2E7A
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist
Shibata, H., Yoshioka, Y., Ohkawa, A., Minowa, K., Mukai, Y., Abe, Y., Taniai, M., Nomura, T., Kayamuro, H., Nabeshi, H., Sugita, T., Imai, S., Nagano, K., Yoshikawa, T., Fujita, T., Nakagawa, S., Yamamoto, A., Ohta, T., Hayakawa, T., Mayumi, T., Vandenabeele, P., Aggarwal, B.B., Nakamura, T., Yamagata, Y., Tsunoda, S., Kamada, H., Tsutsumi, Y.
J.Biol.Chem.
HeaderCytokine
Released2007-01-09
Resolution1.8
CATH Insert Date15 Nov, 2007

PDB Images (7)

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 15 Nov, 2007 Chopped
B 15 Nov, 2007 Chopped
C 15 Nov, 2007 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
2e7aA00 29 Nov, 2007 2.60.120.40 Assigned
2e7aB00 30 Nov, 2007 2.60.120.40 Assigned
2e7aC00 30 Nov, 2007 2.60.120.40 Assigned

Uniprot Entries (3)

Accession Gene ID Taxon Description
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin