PDB Information

PDB2D1X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Hashimoto, S., Hirose, M., Hashimoto, A., Morishige, M., Yamada, A., Hosaka, H., Akagi, K., Ogawa, E., Oneyama, C., Agatsuma, T., Okada, M., Kobayashi, H., Wada, H., Nakano, H., Ikegami, T., Nakagawa, A., Sabe, H.
Proc.Natl.Acad.Sci.Usa
HeaderCell Invasion
Released2005-09-01
Resolution1.900
CATH Insert Date14 Jul, 2006

PDB Images (11)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
B 14 Jul, 2006 Chopped
C 14 Jul, 2006 Chopped
D 14 Jul, 2006 Chopped
P 14 Jul, 2006 Rejected
Q 14 Jul, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2d1xA00 03 Aug, 2007 2.30.30.40 Assigned
2d1xB00 03 Aug, 2007 2.30.30.40 Assigned
2d1xC00 03 Aug, 2007 2.30.30.40 Assigned
2d1xD00 04 Aug, 2007 2.30.30.40 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q9ULH1 ASAP1_HUMAN Homo sapiens Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
Q14247 SRC8_HUMAN Homo sapiens Src substrate cortactin
Q14247 SRC8_HUMAN Homo sapiens Src substrate cortactin
Q14247 SRC8_HUMAN Homo sapiens Src substrate cortactin
Q14247 SRC8_HUMAN Homo sapiens Src substrate cortactin
Q9ULH1 ASAP1_HUMAN Homo sapiens Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1