PDB Information

PDB2CN0
MethodX-RAY DIFFRACTION
Host OrganismCRICETULUS GRISEUS
Gene SourceHOMO SAPIENS
Primary Citation
Mapping the Fluorophilicity of a Hydrophobic Pocket: Synthesis and Biological Evaluation of Tricyclic Thrombin Inhibitors Directing Fluorinated Alkyl Groups Into the P Pocket
Hoffmann-Roder, A., Schweizer, E., Egger, J., Seiler, P., Obst-Sander, U., Wagner, B., Kansy, M., Banner, D.W., Diederich, F.
Chemmedchem
HeaderHydrolase/Hydrolase Inhibitor
Released2006-05-17
Resolution1.300
CATH Insert Date16 Nov, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 16 Nov, 2006 Chopped
I 16 Nov, 2006 Rejected
L 16 Nov, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2cn0H01 24 Jul, 2007 2.40.10.10 Assigned
2cn0H02 24 Jul, 2007 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin