PDB Information

PDB2C8Y
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors
Howard, N., Abell, C., Blakemore, W., Chessari, G., Congreve, M., Howard, S., Jhoti, H., Murray, C.W., Seavers, L.C.A., Van Montfort, R.L.M.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2005-12-08
Resolution2.200
CATH Insert Date18 Jul, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 18 Jul, 2006 Rejected
B 18 Jul, 2006 Chopped
I 18 Jul, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
2c8yB01 18 Oct, 2006 2.40.10.10 Assigned
2c8yB02 18 Oct, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P09945 HIRV2_HIRME Hirudo medicinalis Hirudin variant-2
P00734 THRB_HUMAN Homo sapiens Prothrombin