PDB 2c8x

PDB Links
Overview

PDB Information

PDB	2C8X
Method	X-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation	Application of Fragment Screening and Fragment Linking to the Discovery of Novel Thrombin Inhibitors Howard, N., Abell, C., Blakemore, W., Chessari, G., Congreve, M., Howard, S., Jhoti, H., Murray, C.W., Seavers, L.C.A., Van Montfort, R.L.M. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2005-12-08
Resolution	2.170
CATH Insert Date	18 Jul, 2006

PDB Images (6)

Image of CATH 2c8x

2c8x

PDB 2c8x

Image of CATH 2c8xA

2c8xA

PDB Chain 2c8xA

Image of CATH 2c8xB

2c8xB

PDB Chain 2c8xB

Image of CATH 2c8xI

2c8xI

PDB Chain 2c8xI

Image of CATH 2c8xB01

2c8xB01

CATH Domain 2c8xB01

Image of CATH 2c8xB02

2c8xB02

CATH Domain 2c8xB02

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	18 Jul, 2006	Rejected
B	18 Jul, 2006	Chopped
I	18 Jul, 2006	Rejected

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
2c8xB01	17 Oct, 2006	2.40.10.10	Assigned
2c8xB02	17 Oct, 2006	2.40.10.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P09945	HIRV2_HIRME	Hirudo medicinalis	Hirudin variant-2
P00734	THRB_HUMAN	Homo sapiens	Prothrombin
P00734	THRB_HUMAN	Homo sapiens	Prothrombin