PDB Information

PDB2C6T
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Triazolo[1,5-A]Pyrimidines as Novel Cdk2 Inhibitors: Protein Structure-Guided Design and Sar.
Richardson, C.M., Williamson, D.S., Parratt, M.J., Borgognoni, J., Cansfield, A.D., Dokurno, P., Francis, G.L., Howes, R., Moore, J.D., Murray, J.B., Robertson, A., Surgenor, A.E., Torrance, C.J.
Bioorg.Med.Chem.Lett.
HeaderCell Cycle
Released2005-11-11
Resolution2.610
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2c6tA01 10 Mar, 2006 3.30.200.20 Assigned
2c6tA02 10 Mar, 2006 1.10.510.10 Assigned
2c6tB01 10 Mar, 2006 1.10.472.10 Assigned
2c6tB02 10 Mar, 2006 1.10.472.10 Assigned
2c6tC01 10 Mar, 2006 3.30.200.20 Assigned
2c6tC02 10 Mar, 2006 1.10.510.10 Assigned
2c6tD01 10 Mar, 2006 1.10.472.10 Assigned
2c6tD02 10 Mar, 2006 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2