PDB Information

PDB2AZ5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
Small-molecule inhibition of TNF-alpha.
He, M.M., Smith, A.S., Oslob, J.D., Flanagan, W.M., Braisted, A.C., Whitty, A., Cancilla, M.T., Wang, J., Lugovskoy, A.A., Yoburn, J.C., Fung, A.D., Farrington, G., Eldredge, J.K., Day, E.S., Cruz, L.A., Cachero, T.G., Miller, S.K., Friedman, J.E., Choong, I.C., Cunningham, B.C.
Science
HeaderCytokine
Released2005-09-09
Resolution2.1
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
2az5A00 10 Mar, 2006 2.60.120.40 Assigned
2az5B00 10 Mar, 2006 2.60.120.40 Assigned
2az5C00 10 Mar, 2006 2.60.120.40 Assigned
2az5D00 10 Mar, 2006 2.60.120.40 Assigned

Uniprot Entries (4)

Accession Gene ID Taxon Description
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin
P01375 TNFA_HUMAN Homo sapiens Cachectin