PDB 2acu

PDB Information

PDB2ACU
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.
Bohren, K.M., Grimshaw, C.E., Lai, C.J., Harrison, D.H., Ringe, D., Petsko, G.A., Gabbay, K.H.
Biochemistry
HeaderOxidoreductase
Released1994-04-15
Resolution1.760
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
2acuA00 05 Mar, 2006 3.20.20.100 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P15121 ALDR_HUMAN Homo sapiens Aldo-keto reductase family 1 member B1
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