PDB 2abj

PDB Information

PDB2ABJ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases.
Hu, L.Y., Boxer, P.A., Kesten, S.R., Lei, H.J., Wustrow, D.J., Moreland, D.W., Zhang, L., Ahn, K., Ryder, T.R., Liu, X., Rubin, J.R., Fahnoe, K., Carroll, R.T., Dutta, S., Fahnoe, D.C., Probert, A.W., Roof, R.L., Rafferty, M.F., Kostlan, C.R., Scholten, J.D., Hood, M., Ren, X.D., Schielke, G.P., Su, T.Z., Taylor, C.P., Mistry, A., McConnell, P., Hasemann, C., Ohren, J.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2005-07-15
Resolution2.200
CATH Insert Date14 Jul, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 14 Jul, 2006 Chopped
D 14 Jul, 2006 Chopped
G 14 Jul, 2006 Chopped
J 14 Jul, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
2abjA01 29 Nov, 2006 3.30.470.10 Assigned
2abjA02 29 Nov, 2006 3.20.10.10 Assigned
2abjD01 29 Nov, 2006 3.30.470.10 Assigned
2abjD02 29 Nov, 2006 3.20.10.10 Assigned
2abjG01 30 Nov, 2006 3.30.470.10 Assigned
2abjG02 30 Nov, 2006 3.20.10.10 Assigned
2abjJ01 29 Nov, 2006 3.30.470.10 Assigned
2abjJ02 29 Nov, 2006 3.20.10.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P54687 BCAT1_HUMAN Homo sapiens Branched-chain-amino-acid aminotransferase, cytosolic
P54687 BCAT1_HUMAN Homo sapiens Branched-chain-amino-acid aminotransferase, cytosolic
P54687 BCAT1_HUMAN Homo sapiens Branched-chain-amino-acid aminotransferase, cytosolic
P54687 BCAT1_HUMAN Homo sapiens Branched-chain-amino-acid aminotransferase, cytosolic
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