PDB Information

PDB1ZZ2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes.
Michelotti, E.L., Moffett, K.K., Nguyen, D., Kelly, M.J., Shetty, R., Chai, X., Northrop, K., Namboodiri, V., Campbell, B., Flynn, G.A., Fujimoto, T., Hollinger, F.P., Bukhtiyarova, M., Springman, E.B., Karpusas, M.
Bioorg.Med.Chem.Lett.
HeaderTransferase
Released2005-06-13
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1zz2A01 10 Mar, 2006 3.30.200.20 Assigned
1zz2A02 10 Mar, 2006 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q16539 MK14_HUMAN Homo sapiens Mitogen-activated protein kinase 14