PDB 1ym4

PDB Information

PDB1YM4
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics
Hanessian, S., Yun, H., Hou, Y., Yang, G., Bayrakdarian, M., Therrien, E., Moitessier, N., Roggo, S., Veenstra, S., Tintelnot-Blomley, M., Rondeau, J.M., Ostermeier, C., Strauss, A., Ramage, P., Paganetti, P., Neumann, U., Betschart, C.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2005-01-20
Resolution2.250
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
X 01 Aug, 2011 Rejected
Y 01 Aug, 2011 Rejected
Z 01 Aug, 2011 Rejected

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
1ym4A01 15 Mar, 2006 2.40.70.10 Assigned
1ym4A02 15 Mar, 2006 2.40.70.10 Assigned
1ym4B01 15 Mar, 2006 2.40.70.10 Assigned
1ym4B02 15 Mar, 2006 2.40.70.10 Assigned
1ym4C01 15 Mar, 2006 2.40.70.10 Assigned
1ym4C02 15 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1