PDB 1ygc

PDB Information

PDB1YGC
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
Olivero, A.G., Eigenbrot, C., Goldsmith, R., Robarge, K., Artis, D.R., Flygare, J., Rawson, T., Sutherlin, D.P., Kadkhodayan, S., Beresini, M., Elliott, L.O., DeGuzman, G.G., Banner, D.W., Ultsch, M., Marzec, U., Hanson, S.R., Refino, C., Bunting, S., Kirchhofer, D.
J.Biol.Chem.
HeaderHydrolase
Released2005-01-04
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
L 05 Mar, 2006 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1ygcH01 21 Oct, 2006 2.40.10.10 Assigned
1ygcH02 21 Oct, 2006 2.40.10.10 Assigned
1ygcL00 10 Mar, 2006 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII