PDB Information

PDB1YCP
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Crystal structure of fibrinogen-Aalpha peptide 1-23 (F8Y) bound to bovine thrombin explains why the mutation of Phe-8 to tyrosine strongly inhibits normal cleavage at Arg-16.
Malkowski, M.G., Martin, P.D., Lord, S.T., Edwards, B.F.
Biochem.J.
HeaderHydrolase/Hydrolase Substrate
Released1997-05-01
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (12)

PDB Prints

PDB Chains (7)

Chain ID Date inserted into CATH CATH Status
F 05 Mar, 2006 Rejected
H 05 Mar, 2006 Chopped
J 05 Mar, 2006 Rejected
K 05 Mar, 2006 Chopped
L 05 Mar, 2006 Rejected
M 05 Mar, 2006 Chopped
N 05 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1ycpH01 05 Mar, 2006 2.40.10.10 Assigned
1ycpH02 05 Mar, 2006 2.40.10.10 Assigned
1ycpK00 05 Mar, 2006 2.40.10.10 Assigned
1ycpM00 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (7)

Accession Gene ID Taxon Description
P00735 THRB_BOVIN Bos taurus Prothrombin
P00735 THRB_BOVIN Bos taurus Prothrombin
P00735 THRB_BOVIN Bos taurus Prothrombin
P00735 THRB_BOVIN Bos taurus Prothrombin
P00735 THRB_BOVIN Bos taurus Prothrombin
P02671 FIBA_HUMAN Homo sapiens Fibrinogen alpha chain
P02671 FIBA_HUMAN Homo sapiens Fibrinogen alpha chain