PDB Information

PDB1XN2
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21
Gene SourceHomo sapiens
Primary Citation
Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Turner III, R.T., Hong, L., Koelsch, G., Ghosh, A.K., Tang, J.
Biochemistry
HeaderHydrolase/Hydrolase Inhibitor
Released2004-10-04
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Rejected
F 05 Mar, 2006 Rejected
G 05 Mar, 2006 Rejected
H 05 Mar, 2006 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
1xn2A01 09 Mar, 2006 2.40.70.10 Assigned
1xn2A02 09 Mar, 2006 2.40.70.10 Assigned
1xn2B01 09 Mar, 2006 2.40.70.10 Assigned
1xn2B02 09 Mar, 2006 2.40.70.10 Assigned
1xn2C01 09 Mar, 2006 2.40.70.10 Assigned
1xn2C02 09 Mar, 2006 2.40.70.10 Assigned
1xn2D01 09 Mar, 2006 2.40.70.10 Assigned
1xn2D02 09 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1
P56817 BACE1_HUMAN Homo sapiens Beta-secretase 1