PDB Information

PDB1VR1
MethodX-RAY DIFFRACTION
Host OrganismCricetinae gen. sp.
Gene SourceHomo sapiens
Primary Citation
The variable region-1 from tissue-type plasminogen activator confers specificity for plasminogen activator inhibitor-1 to thrombin by facilitating catalysis: release of a kinetic block by a heterologous protein surface loop
Dekker, R.J., Eichinger, A., Stoop, A.A., Bode, W., Pannekoek, H., Horrevoets, A.J.G.
J.Mol.Biol.
HeaderBlood Clotting/Hydrolase Inhibitor
Released1998-12-11
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1vr1H01 05 Mar, 2006 2.40.10.10 Assigned
1vr1H02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P28504 HIR2_HIRME Hirudo medicinalis Hirudin-2
P00734 THRB_HUMAN Homo sapiens Prothrombin