PDB 1uk1

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Overview

PDB Information

PDB	1UK1
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase Hattori, K., Kido, Y., Yamamoto, H., Ishida, J., Kamijo, K., Murano, K., Ohkubo, M., Kinoshita, T., Iwashita, A., Mihara, K., Yamazaki, S., Matsuoka, N., Teramura, Y., Miyake, H. J.Med.Chem.
Header	Transferase
Released	2003-08-14
Resolution	3.000
CATH Insert Date	05 Mar, 2006

PDB Images (7)

Image of CATH 1uk1

1uk1

PDB 1uk1

Image of CATH 1uk1A

1uk1A

PDB Chain 1uk1A

Image of CATH 1uk1B

1uk1B

PDB Chain 1uk1B

Image of CATH 1uk1A01

1uk1A01

CATH Domain 1uk1A01

Image of CATH 1uk1A02

1uk1A02

CATH Domain 1uk1A02

Image of CATH 1uk1B01

1uk1B01

CATH Domain 1uk1B01

Image of CATH 1uk1B02

1uk1B02

CATH Domain 1uk1B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1uk1A01	05 Mar, 2006	1.20.142.10	Assigned
1uk1A02	05 Mar, 2006	3.90.228.10	Assigned
1uk1B01	05 Mar, 2006	1.20.142.10	Assigned
1uk1B02	05 Mar, 2006	3.90.228.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1
P09874	PARP1_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase 1