PDB 1tt5

PDB Information

PDB1TT5
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli BL21(DE3)
Gene SourceHomo sapiens
Primary Citation
A unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8.
Huang, D.T., Miller, D.W., Mathew, R., Cassell, R., Holton, J.M., Roussel, M.F., Schulman, B.A.
Nat.Struct.Mol.Biol.
HeaderCell Cycle, Ligase
Released2004-06-21
Resolution2.600
CATH Insert Date05 Mar, 2006

PDB Images (17)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped
E 05 Mar, 2006 Rejected
F 05 Mar, 2006 Rejected

CATH Domains (10)

Domain ID Date inserted into CATH Superfamily CATH Status
1tt5A01 18 Aug, 2007 3.40.50.720 Assigned
1tt5A02 18 Aug, 2007 Holding pen
1tt5B01 09 Mar, 2006 3.40.50.720 Assigned
1tt5B02 09 Mar, 2006 1.10.10.520 Assigned
1tt5B03 09 Mar, 2006 3.10.20.260 Assigned
1tt5C01 18 Aug, 2007 3.40.50.720 Assigned
1tt5C02 18 Aug, 2007 Holding pen
1tt5D01 05 Mar, 2006 3.40.50.720 Assigned
1tt5D02 05 Mar, 2006 1.10.10.520 Assigned
1tt5D03 05 Mar, 2006 3.10.20.260 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
Q13564 ULA1_HUMAN Homo sapiens NEDD8-activating enzyme E1 regulatory subunit
P61081 UBC12_HUMAN Homo sapiens NEDD8-conjugating enzyme Ubc12
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit
P61081 UBC12_HUMAN Homo sapiens NEDD8-conjugating enzyme Ubc12
Q8TBC4 UBA3_HUMAN Homo sapiens NEDD8-activating enzyme E1 catalytic subunit