PDB Information

PDB1T7I
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Discovery and selection of TMC114, a next generation HIV-1 protease inhibitor
Surleraux, D.L.N.G., Tahri, A., Verschueren, W.G., Pille, G.M.E., de Kock, H.A., Jonckers, T.H.M., Peeters, A., De Meyer, S., Azijn, H., Pauwels, R., de Bethune, M.-P., King, N.M., Prabu-Jeyabalan, M., Schiffer, C.A., Wigerinck, P.B.T.P.
J.Med.Chem.
HeaderHydrolase
Released2004-05-10
Resolution1.350
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1t7iA00 09 Mar, 2006 2.40.70.10 Assigned
1t7iB00 09 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P35963 POL_HV1Y2 Human immunodeficiency virus type 1 (isolate YU2) Gag-Pol polyprotein
P35963 POL_HV1Y2 Human immunodeficiency virus type 1 (isolate YU2) Gag-Pol polyprotein