PDB Information

PDB1SUQ
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants
Das, K., Clark Jr., A.D., Lewi, P.J., Heeres, J., De Jonge, M.R., Koymans, L.M., Vinkers, H.M., Daeyaert, F., Ludovici, D.W., Kukla, M.J., De Corte, B., Kavash, R.W., Ho, C.Y., Ye, H., Lichtenstein, M.A., Andries, K., Pauwles, R., Debethune, M.-P., Boyer, P.L., Clark, P., Hughes, S.H., Janssen, P.A., Arnold, E.
J.Med.Chem.
HeaderTransferase
Released2004-03-26
Resolution3.000
CATH Insert Date05 Mar, 2006

PDB Images (12)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (9)

Domain ID Date inserted into CATH Superfamily CATH Status
1suqA01 05 Mar, 2006 3.10.10.10 Assigned
1suqA02 05 Mar, 2006 3.30.70.270 Assigned
1suqA03 05 Mar, 2006 3.30.70.270 Assigned
1suqA04 05 Mar, 2006 3.30.70.270 Assigned
1suqA05 05 Mar, 2006 3.30.420.10 Assigned
1suqB01 09 Mar, 2006 3.10.10.10 Assigned
1suqB02 09 Mar, 2006 3.30.70.270 Assigned
1suqB03 09 Mar, 2006 3.30.70.270 Assigned
1suqB04 09 Mar, 2006 3.30.70.270 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein
P03366 POL_HV1B1 Human immunodeficiency virus type 1 BH10 Gag-Pol polyprotein