PDB Information

PDB1OIU
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
N2-Substituted O6-Cyclohexylmethylguanine Derivatives: Potent Inhibitors of Cyclin-Dependent Kinases 1 and 2
Hardcastle, I.R., Arris, C.E., Bentley, J., Boyle, F.T., Chen, Y., Curtin, N.J., Endicott, J.A., Gibson, A.E., Golding, B.T., Griffin, R.J., Jewsbury, P., Menyerol, J., Mesguiche, V., Newell, D.R., Noble, M.E.M., Pratt, D.J., Wang, L.-Z., Whitfield, H.J.
J.Med.Chem.
HeaderKinase
Released2003-06-26
Resolution2.000
CATH Insert Date05 Mar, 2006

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
1oiuA01 05 Mar, 2006 3.30.200.20 Assigned
1oiuA02 05 Mar, 2006 1.10.510.10 Assigned
1oiuB01 05 Mar, 2006 1.10.472.10 Assigned
1oiuB02 05 Mar, 2006 1.10.472.10 Assigned
1oiuC01 05 Mar, 2006 3.30.200.20 Assigned
1oiuC02 05 Mar, 2006 1.10.510.10 Assigned
1oiuD01 05 Mar, 2006 1.10.472.10 Assigned
1oiuD02 05 Mar, 2006 1.10.472.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2
P20248 CCNA2_HUMAN Homo sapiens Cyclin-A2