PDB Information

PDB1NQL
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
EGF activates its receptor by removing interactions that auto-inhibit ectodomain dimerization
Ferguson, K.M., Berger, M.B., Mendrola, J.M., Cho, H., Leahy, D.J., Lemmon, M.A.
Mol.Cell
HeaderHormone/Growth Factor Receptor
Released2003-01-21
Resolution2.800
CATH Insert Date05 Mar, 2006

PDB Images (8)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (5)

Domain ID Date inserted into CATH Superfamily CATH Status
1nqlA01 28 Aug, 2007 3.80.20.20 Assigned
1nqlA02 28 Aug, 2007 2.10.220.10 Assigned
1nqlA03 28 Aug, 2007 3.80.20.20 Assigned
1nqlA04 28 Aug, 2007 2.10.220.10 Assigned
1nqlB00 05 Mar, 2006 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P01133 EGF_HUMAN Homo sapiens Pro-epidermal growth factor
P00533 EGFR_HUMAN Homo sapiens Epidermal growth factor receptor