PDB Information

PDB1NH3
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structural Impact of the Leukemia Drug 1-beta-D-Arabinofuranosylcytosine (Ara-C) on the Covalent Human Topoisomerase I-DNA Complex
Chrencik, J.E., Burgin, A.B., Pommier, Y., Stewart, L., Redinbo, M.R.
J.Biol.Chem.
HeaderIsomerase/Dna
Released2002-12-18
Resolution3.100
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 15 Mar, 2006 Rejected
C 15 Mar, 2006 Rejected
D 15 Mar, 2006 Rejected

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1nh3A01 08 Mar, 2006 1.10.10.41 Assigned
1nh3A02 08 Mar, 2006 2.170.11.10 Assigned
1nh3A03 08 Mar, 2006 3.90.15.10 Assigned
1nh3A04 08 Mar, 2006 1.10.132.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11387 TOP1_HUMAN Homo sapiens DNA topoisomerase 1