PDB Information

PDB1LXC
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI).
Miller, W.H., Seefeld, M.A., Newlander, K.A., Uzinskas, I.N., Burgess, W.J., Heerding, D.A., Yuan, C.C., Head, M.S., Payne, D.J., Rittenhouse, S.F., Moore, T.D., Pearson, S.C., Berry, V., DeWolf Jr., W.E., Keller, P.M., Polizzi, B.J., Qiu, X., Janson, C.A., Huffman, W.F.
J.Med.Chem.
HeaderOxidoreductase
Released2002-06-05
Resolution2.400
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1lxcA00 05 Mar, 2006 3.40.50.720 Assigned
1lxcB00 05 Mar, 2006 3.40.50.720 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0AEK4 FABI_ECOLI Escherichia coli K-12 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI
P0AEK4 FABI_ECOLI Escherichia coli K-12 Enoyl-[acyl-carrier-protein] reductase [NADH] FabI