PDB 1ld8

PDB Links
Overview

PDB Information

PDB	1LD8
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	3-Aminopyrrolidinone farnesyltransferase inhibitors: design of macrocyclic compounds with improved pharmacokinetics and excellent cell potency. Bell, I.M., Gallicchio, S.N., Abrams, M., Beese, L.S., Beshore, D.C., Bhimnathwala, H., Bogusky, M.J., Buser, C.A., Culberson, J.C., Davide, J., Ellis-Hutchings, M., Fernandes, C., Gibbs, J.B., Graham, S.L., Hamilton, K.A., Hartman, G.D., Heimbrook, D.C., Homnick, C.F., Huber, H.E., Huff, J.R., Kassahun, K., Koblan, K.S., Kohl, N.E., Lobell, R.B., Lynch Jr., J.J., Robinson, R., Rodrigues, A.D., Taylor, J.S., Walsh, E.S., Williams, T.M., Zartman, C.B. J.Med.Chem.
Header	Transferase
Released	2002-04-08
Resolution	1.800
CATH Insert Date	05 Mar, 2006

PDB Images (5)

Image of CATH 1ld8

1ld8

PDB 1ld8

Image of CATH 1ld8A

1ld8A

PDB Chain 1ld8A

Image of CATH 1ld8B

1ld8B

PDB Chain 1ld8B

Image of CATH 1ld8A00

1ld8A00

CATH Domain 1ld8A00

Image of CATH 1ld8B00

1ld8B00

CATH Domain 1ld8B00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1ld8A00	05 Mar, 2006	1.25.40.120	Assigned
1ld8B00	05 Mar, 2006	1.50.10.20	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P49354	FNTA_HUMAN	Homo sapiens	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
P49356	FNTB_HUMAN	Homo sapiens	Protein farnesyltransferase subunit beta